Modern approaches to diagnosis and treatment of early-onset neonatal sepsis

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Epidemiologic features of early onset sepsis in neonatal ward of Shabih Khani hospital in Kashan

Background and objective: Neonatal sepsis is defined as presence of clinical signs accompanied by positive blood culture in newborns less than one month of age. Sepsis is a common cause of hospital admission in neonates, and it is known as one of the main causes of mortality among them, not only in developed countries but in developing ones. Delay in diagnosis and appropriate antibiotic therapy...

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Early Onset Neonatal Sepsis and Meningitis.

Brief History of the Present Illness A 6-day-old female with septic shock was admitted to the hospital in the fall. Two days before admission, she had developed a macular rash on her face and extremities that was attributed to a normal newborn rash. She also had difficulty with breastfeeding, and her mother started formula supplementation upon suggestion by her pediatrician. Over the next 48 ho...

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Early-onset neonatal sepsis: cord blood cytokine levels at diagnosis and during treatment.

OBJECTIVE To assess clinical and laboratory parameters and serum cytokine levels in 55 neonates who developed early-onset sepsis. METHODS Clinical parameters associated with early-onset neonatal sepsis were assessed. White blood cell differential and serum C-reactive protein and glucose levels were measured upon diagnosis of sepsis and 48 hours later. IL-beta, IL-10, IL-6, and TNF-α levels we...

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Epidemiology of Neonatal Early-onset Sepsis

Neonatal early-onset sepsis (EOS) continues to be a significant source of morbidity and mortality among newborns, especially among very-low birthweight infants. Epidemiologic risk factors for EOS have been defined, and considerable resources are devoted to the identification and evaluation of infants at risk for EOS. The widespread implementation of intrapartum antibiotic prophylaxis for the pr...

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ژورنال

عنوان ژورنال: ScienceRise: Medical Science

سال: 2020

ISSN: 2519-4798,2519-478X

DOI: 10.15587/2519-4798.2020.209137